Vitamin D Status in Diabetes Mellitus: Comparison Between Outpatients and Inpatients
Abstract:
Objectives:
Vitamin D (25(OH)D) status has been extensively evaluated in different populations and care settings. A negative relationship between glycated hemoglobin (HbA1c) and serum 25(OH)D levels in outpatients with diabetes has been reported, while data about 25(OH)D status in inpatients with diabetes are inconsistent. The aim of the study was to evaluate 25(OH)D levels in a large series of inpatients with type 1 and type 2 diabetes and in an age-, sex-, serum creatinine-, and HbA1c-matched group of outpatients with diabetes.
Design:
After the preliminary exclusion of patients with confounding factors, 540 subjects with diabetes were retrospectively evaluated in a 1:1 matched case-control study between inpatients and outpatients.
Results: </t...</p>
<a class="btn btn-primary blue-btn text-uppercase my-4" href="https://www.oap-researchhub.org/preventive-medicine-and-care/article/vitamin-d-status-in-diabetes-mellitus-comparison-between-outpatients-and-inpatients-514">Read Article</a>
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<h4 class="article-title title-border pb-3"> Multivariate Analysis of Noise, Socioeconomic and Sociodemographic Factors and Their Association with Depression on Borough Level in the City State of Hamburg, Germany </h4>
<h4 class="article-title fw-700">Abstract:</h4>
<p><abstract>
<p>The objective of this first part of our study was to investigate associations of road traffic noise, socioeconomic and -demographic risk factors, and health access on depression on borough level.</p>
<p>We investigated in a large metropolis associations between prevalence rates of depression per borough (n = 67 boroughs) in all age groups (excluding the age group of 0–17 years) using health claims data (year 2011) and the variables “social deprivation” and “number of family members”, which were obtained from a previously conducted principal component analysis, and by using multivariate regression model. Additionally, the proportion of borough area affected by noise > 65 db(A) and physician density used as a surrogate parameter for health access were considered as potentially associated factors for depression. </p>
<p>The results demonstrated that depression might be associated with increasing social borough deprivation. ...</p>
<a class="btn btn-primary blue-btn text-uppercase my-4" href="https://www.oap-researchhub.org/depression-and-therapy/article/multivariate-analysis-of-noise-socioeconomic-and-sociodemographic-factors-and-their-association-with-depression-on-borough-level-in-the-city-515">Read Article</a>
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<h4 class="article-title title-border pb-3"> Relationship Between Inflammatory Infiltrate Canine Mammary Carcinomas.</h4>
<h4 class="article-title fw-700">Abstract:</h4>
<p><abstract>
<p>The mammary tumor is one of the most common cancer in female dogs and, at the present days, there is a big focus on the study of the relation between this kind of tumor in animals and the cells that stay around them, like the inflammatory cells. The objective of this study was to evaluate and show where the inflammatory cells stay in simple mammary carcinomas in female dogs by immunohistochemistry. Samples of simple mammary carcinomas (tumor group; n=26) and mammary gland samples without tumor (control group; n=18) were submitted to immunohistochemical analysis for the detection of T lymphocytes, macrophages, plasma cells and the MHC-II molecule. The mast cells were evaluated by the histochemical technique (toluidine blue). Lymphocytes, macrophages and mast cells were observed distributed in the tumor stroma. MHC-II was detected in tumor cells and in the inflammatory infiltrate. Plasma cells predominated in the peritumoral stroma. Macrophages differed significantl...</p>
<a class="btn btn-primary blue-btn text-uppercase my-4" href="https://www.oap-researchhub.org/veterinary-healthcare/article/relationship-between-inflammatory-infiltrate-canine-mammary-carcinomas-518">Read Article</a>
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<h4 class="article-title title-border pb-3"> Shotgun Label-Free Proteomic Analyses of the Oyster Parasite Perkinsus Marinus</h4>
<h4 class="article-title fw-700">Abstract:</h4>
<p><abstract>
<p>Perkinsus marinus is an intracellular parasitic protozoan that is responsible for serious disease epizootics in marine bivalve mollusks worldwide. Despite all available information on P. marinus genomics, more baseline data is required at the proteomic level. Our aim was to study the proteome profile of in vitro cultured P. marinus isolated from oysters Crassostrea spp. using a label-free shotgun UDMSE approach. A total of 4073 non-redundant proteins were identified across three biological replicates with stringent identification. Proteins specifically related to adaptive survival, cell recognition, antioxidants, regulation of apoptosis and others were detected. Important virulence factors of P. marinus were identified including serine protease and iron-dependent superoxide dismutase. Other proteins with involvement in several pathogens invasion strategies were rhoptries, serine-threonine kinases, and protein phosphatases. Interestingly, peptides corresponding to ...</p>
<a class="btn btn-primary blue-btn text-uppercase my-4" href="https://www.oap-researchhub.org/proteomics-and-genomics-research/article/shotgun-label-free-proteomic-analyses-of-the-oyster-parasite-perkinsus-marinus-519">Read Article</a>
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<h4 class="article-title title-border pb-3"> Pharmaceutical intervention on Ca2+/cAMP signaling interaction: benefits for combating neurodegeneration and diseases related to aging </h4>
<h4 class="article-title fw-700">Abstract:</h4>
<p><abstract>
<p>This review explores crosstalk between Ca2+ and cAMP signaling and its therapeutic implications for neurodegeneration and aging. It summarizes candidate interventions and translational challenges.</p>
</abstract>...</p>
<a class="btn btn-primary blue-btn text-uppercase my-4" href="https://www.oap-researchhub.org/international-journal-of-human-anatomy/article/pharmaceutical-intervention-on-ca2-camp-signaling-interaction-benefits-for-combating-neurodegeneration-and-diseases-related-to-aging-508">Read Article</a>
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<h4 class="article-title title-border pb-3"> Drawbacks of Long-Acting Intramuscular Antipsychotic Injections</h4>
<h4 class="article-title fw-700">Abstract:</h4>
<p><abstract>
<p>Second-generation antipsychotics have relatively recently become available in long-acting intramuscular formulations (LAIs) and have been receiving a substantial amount of pharmaceutical industry promotion on the grounds that they improve treatment adherence in patients with psychotic illness. LAIs do have some drawbacks, however, which is the topic area covered by this review. A Global Scholar search of the nursing and medical literature reveals several factors that can negatively impinge on the clinical efficacy of LAIs: 1. The extent of training of injection personnel 2. The quality of surveillance of patient symptoms and side effects 3. The skilled use of the full range of injection techniques 4. The extent of drug accumulation over time 5. The potential loss of drug dose flexibility 6. The impact of exercise and temperature on drug distribution 7. The burden of the medication routine and the social burdens of LAIs 8. The safety of LAIs during pregnancy 9. The...</p>
<a class="btn btn-primary blue-btn text-uppercase my-4" href="https://www.oap-researchhub.org/clinical-and-practical-nursing/article/drawbacks-of-long-acting-intramuscular-antipsychotic-injections-510">Read Article</a>
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<h4 class="article-title title-border pb-3"> Thymic Hypertrophy and Sudden Unexpected Death In Adults –A Retrospective Study Of 56 Autopsy Cases</h4>
<h4 class="article-title fw-700">Abstract:</h4>
<p><abstract>
<p>Status thymico-lymphaticus had ever been explained as a cause of sudden death usually in children, but few cases were reported in adults. We sought to determine the relationship between thymic hypertrophy and sudden unexpected death in adult (SUDA), and associated macroscopic and microscopic findings. Adult post mortems from 1984 to 2014 were reviewed and 23 thymic hypertrophy patients without SUDA, 33 thymic hypertrophy patients with SUDA and 172 SUDAs without thymic hypertrophy entered. The data of thymus, lymph nodes, spleen, heart, aorta, and adrenal glands were collected for macroscopic and histological analysis. Ten antibodies were used and applied to 3 children and 46 adult thymus specimens. We found, as an independent factor, thymic hypertrophy increased significantly the risk of SUDA (6.9 folds) in both male and female. What’s more, SUDAs associated with thymic hypertrophy were quite younger (22.5 years) than those without it. A majority of patients wit...</p>
<a class="btn btn-primary blue-btn text-uppercase my-4" href="https://www.oap-researchhub.org/international-journal-of-human-anatomy/article/thymic-hypertrophy-and-sudden-unexpected-death-in-adults-a-retrospective-study-of-56-autopsy-cases-511">Read Article</a>
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email: con_email,
message: message,
website: $("#home_contact_website").val() || '',
form_started_at: $("#home_contact_form_started_at").val() || homeContactStartedAt,
'g-recaptcha-response': token
};
if (homeContactCsrfToken && homeContactCsrfHash) {
payload[homeContactCsrfToken] = homeContactCsrfHash;
}
$.ajax({
url: "https://www.oap-researchhub.org/Home/submit_contact_us_home",
data: payload,
type: "POST",
dataType: "json",
success:function(data){
var response = typeof data === "string" ? JSON.parse(data) : data;
var status = response.status || "Failed";
var responseMessage = response.message || "";
updateHomeContactCsrf(response.csrf || null);
if (status === "Success") {
setHomeContactStatus("success", "Message sent", "Thanks. Your message has been sent to Open Access Pub. Our support team will reply as soon as possible.");
$("#con_name, #con_email, #message_textare").val("");
} else {
setHomeContactStatus("error", "Message was not sent", responseMessage || "Please try again or email info@openaccesspub.org.");
}
refreshHomeContactGuards();
},
error:function (){
setHomeContactStatus("error", "Message was not sent", "Please try again or email info@openaccesspub.org.");
refreshHomeContactGuards();
},
complete:function (){
submitButton.prop("disabled", false).text(submitButton.data("default-text") || "Send");
}
});
};
loadHomeContactRecaptcha(function(homeContactRecaptchaClient) {
if (!homeContactRecaptchaClient) {
sendHomeContact('');
return;
}
homeContactRecaptchaClient.ready(function() {
homeContactRecaptchaClient.execute(homeContactRecaptchaSiteKey, {action: 'contact_us_home'}).then(function(token) {
sendHomeContact(token);
}, function() {
setHomeContactStatus("error", "Security verification failed", "Please try again.");
refreshHomeContactGuards();
submitButton.prop("disabled", false).text(submitButton.data("default-text") || "Send");
});
});
}, function() {
setHomeContactStatus("error", "Security verification unavailable", "Please refresh the page and try again.");
refreshHomeContactGuards();
submitButton.prop("disabled", false).text(submitButton.data("default-text") || "Send");
});
return false;
});
function setHomeContactStatus(type, title, message) {
var statusBox = $("#mail-status");
var safeTitle = $("<div>").text(title).html();
var safeMessage = $("<div>").text(message).html();
statusBox
.removeClass("is-success is-error is-info")
.addClass("is-" + type)
.html('<div class="home-contact-alert"><strong>' + safeTitle + '</strong><span>' + safeMessage + '</span></div>')
.attr("tabindex", "-1")
.focus();
}
function resetHomeContactFields() {
$("#con_name, #con_email, #message_textare").removeClass("home-contact-field-error");
}
function isEmail(email) {
var regex = /^[^\s@]+@[^\s@]+\.[^\s@]+$/;
return regex.test(email);
}
$("#send-email-form").on("submit",function(){
$.ajax({
type: "POST",
url: "https://www.oap-researchhub.org/journal/submit_email",
data: {fname: $("#fname").val(),lname: $("#lname").val(),sname:$("#sname").val(), subject: $("#subject").val(),email: $("#email").val(),message: $("#message").val(),journal_title:$("#journal_title").val(),edt_name:$('#edt_name').val()},
dataType: "text",
success: function(data){
$('#success_text').html("Email Sent Successfully");
$('#success_text').show();
document.getElementById("send-email-form").reset();
},
error: function() { alert("Something went wrong..."); }
});
return false;
});
});
</script>
<script>
let scrollRef = 0;
window.addEventListener('scroll', function() {
scrollRef <= 10 ? scrollRef++ : AOS.refresh();
})
$(document).ready(function() {
$(document).on('click', function (event) {
var checkshow= $("#navbarCollapse").hasClass("show");
var checkjmenu= $(".inner-menu").hasClass("Jmmenu");
if(checkshow || checkjmenu){
$("#navbarCollapse").removeClass('show');
$(".inner-menu").removeClass('Jmmenu');
$('button.btn.filterbtn span').html("+");
}});
$('.filterbtn').on('click', function (event) {
event.stopPropagation();
});
});
</script>
<script>
if (window.location.hostname === 'staging.openaccesspub.org') {
document.addEventListener('click', function (event) {
const link = event.target.closest('a[href]');
if (!link) {
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}
const href = link.getAttribute('href') || '';
if (!href || href.startsWith('#') || href.startsWith('javascript:')) {
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const target = new URL(link.href, window.location.origin);
const blockedHost = target.hostname === 'openaccesspub.org'
|| target.hostname === 'www.openaccesspub.org';
if (blockedHost && target.hostname !== window.location.hostname) {
event.preventDefault();
alert('This link is disabled on staging.');
}
});
}
</script>
</body></html>